Infection-acquired immunity

Egg-Head Jabid Gets Egg All Over His Face At King’s College NHS

He visited King’s College London Hospital today and asked the question, what do staff think of the vaccine mandates being introduced. If looks could kill. But the nurses remained silent. Consultant Dr Steve James didn’t though:

Ouch! Jabid looked suddenly stupid and way out of his depth. But he still managed to insult an experienced professional medic by suggesting that his facts were merely opinion and by stating that the government relied on the very best advice of ‘vaccine experts’. Yeah, we know the kind of ‘experts’ he’s talking about. Billionaire computer geeks, former war criminal PMs, hopelessly compromised Chief Medical Officers, the WEF, hard sell Pfizer vaccine salesmen, etc. Even when they receive actual expert advice from panels like the JCVI, who advised against jabbing kids, they ignore it.

Bob Moran sums up Jabid’s spanking at King’s quite nicely:

Now, in case you were wondering if Jabid is actually the scientifically illiterate, factually challenged, arrogant little egg-headed turd that he comes across as, here is the evidence. In response to Dr James arguing that ‘vaccine’ effectiveness tended to wane very quickly and it was impractical to keep giving staff boosters every month or so, Jabid claimed that infection-acquired antibodies waned also. Well, yes, that’s what they do. It’s entirely natural. Jabid appears not to understand at all what naturally acquired immunity actually is. Because what happens is, with a mild to moderate, even severe infection, the body produces antibodies in the blood and the lymph to fight the virus. These antibodies don’t just target the spike region (as do the ‘vaccines’); they target other parts of the virus too, meaning that the antibody response is broad spectrum.

What then happens is that once the viral infection is defeated, these humoral antibodies naturally decline and eventually all but disappear. However, this does not mean that the immune system cannot see off another attack by the same virus, because the immune cells retain a memory of the virus, such that fresh antibodies can be produced rapidly if the body is challenged again by infection. This Nature article explains:

Many people who have been infected with SARS-CoV-2 will probably make antibodies against the virus for most of their lives. So suggest researchers who have identified long-lived antibody-producing cells in the bone marrow of people who have recovered from COVID-191.

The study provides evidence that immunity triggered by SARS-CoV-2 infection will be extraordinarily long-lasting.

Antibodies — proteins that can recognize and help to inactivate viral particles — are a key immune defence. After a new infection, short-lived cells called plasmablasts are an early source of antibodies.

But these cells recede soon after a virus is cleared from the body, and other, longer-lasting cells make antibodies: memory B cells patrol the blood for reinfection, while bone marrow plasma cells (BMPCs) hide away in bones, trickling out antibodies for decades.

“A plasma cell is our life history, in terms of the pathogens we’ve been exposed to,” says Ali Ellebedy, a B-cell immunologist at Washington University in St. Louis, Missouri, who led the study, published in Nature on 24 May.

Ellebedy’s team tracked antibody production in 77 people who had recovered from mostly mild cases of COVID-19. As expected, SARS-CoV-2 antibodies plummeted in the four months after infection. But this decline slowed, and up to 11 months after infection, the researchers could still detect antibodies that recognized the SARS-CoV-2 spike protein.

To identify the source of the antibodies, Ellebedy’s team collected memory B cells and bone marrow from a subset of participants. Seven months after developing symptoms, most of these participants still had memory B cells that recognized SARS-CoV-2. In 15 of the 18 bone-marrow samples, the scientists found ultra-low but detectable populations of BMPCs whose formation had been triggered by the individuals’ coronavirus infections 7–8 months before. Levels of these cells were stable in all five people who gave another bone-marrow sample several months later.

“This is a very important observation,” given claims of dwindling SARS-CoV-2 antibodies, says Rafi Ahmed, an immunologist at Emory University in Atlanta, Georgia, whose team co-discovered the cells in the late 1990s.

If Jabid doesn’t know this, then he isn’t fit to be health secretary. Of course, Nature being what it is, it cannot give the impression that natural immunity is superior in any way to vaccine immunity – although several studies show that it is – so it states the caveat that even memory cell mediated infection-acquired immunity to SARS-CoV-2 might not last for years. Bizarrely, this contradicts its earlier statements that infection-acquired immunity probably lasts a lifetime. Well, it might not last a lifetime, but with SARS 1, infection-acquired immunity was shown to be still effective after 17 years, so I’d say that was pretty long lasting naturally acquired immunity to a virus genetically very similar to SARS-CoV-2.

What’s not clear is what antibody levels will look like in the long term and whether they offer any protection, Ahmed adds. “We’re early in the game. We’re not looking at five years, ten years after infection.”

Ellebedy’s team has observed early signs that Pfizer’s mRNA vaccine should trigger the production of the same cells4. But the persistence of antibody production, whether elicited by vaccination or by infection, does not ensure long-lasting immunity to COVID-19. The ability of some emerging SARS-CoV-2 variants to blunt the protective effects of antibodies means that additional immunizations may be needed to restore levels, says Ellebedy. “My presumption is, we will need a booster.”

The other obvious point to make is that Ellebedy probably means an annual booster, not a flipping booster every month or two, as is currently being proposed by power mad governments and insane medical officers, and which is actually happening (to little effect) in Israel for instance, who are now onto the fourth jab.

So a big congratulations to Dr Steve James for speaking up in defence of logic and science and revealing Jabid for what he is. let’s hope Kings NHS Trust don’t sack him for his bravery.